Tumour Necrosis Factor Inhibitors For Inflammatory Bowel Disease
31792 01/21/2015 Health Care 217 /An effective drug that inhibits responses to TNF related inflammations and cell death, TNF inhibitor are made use of in the treatment of several diseases like rheumatoid arthritis, spondylitis, inflammatory bowel diseases, and psoriasis. Monoclonal antibodies like infliximab, adalimumab, and golimumab are widely used to achieve TNF inhibition. Apart from monoclonal antibodies, simple molecules such as xanthine derivatives and bupropion are also used as TNF inhibitors.
What is TNF antagonist?
Does the word ‘TNF antagonist’ sounds too much complex and undecipherable? This post will help you find adequate info on what it is all about!
Technically put, TNF antagonists/inhibitors are pharmaceutical drugs that are prescribed to help inhibit the response to TNF, which is a crucial part of inflammatory response. TNF is a major factor that triggers auto-immune disorders, including arthritis, spondylosis, and IBD. Anti TNF drugs have been widely recommended to treat inflammatory conditions that are caused as a result of these aforesaid diseases. These drugs not only help reduce inflammation, but also help curb the quick progression of the disease. Here are a few quick facts on the most commonly used Anti TNF drugs:
1. Anti-TNF drugs mainly target the inflammation-causing agent called TNF.
2. Anti-TNF drugs can be used to treat several diseases, including IBD and arthritis.
3. They can help successfully control the inflammation in joints, gastrointestinal tract and skin.
According to experts, 5 anti-TNF drugs have been approved by the U.S. Food and Drug Administration. These well-known drugs have been widely used or the treatment of various diseases likearthritis, spondylosis, and IBD. However, in order to decrease the side effects, anti TNF drugs are recommended in mild quantities, along with optimal use of methotrexate, hydroxychloroquine, leflunomide or sulfasalazine.
Need more information on Anti-TNF drugs? Keep reading some of the top research journals out there online!
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